Startle Response System: SR-LAB™

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The world’s most widely used startle response system.
SR-LAB™ startle response system is your best choice for startle reflex testing. The system’s design ensures accurate results for all paradigms. You will not be limited by the software to any specific paradigms, either—it supports any paradigm while ensuring your data is saved in a single-file for easy retrieval and export.

Test up to 16 animals at one time in SDI’s unique tubular enclosures which eliminate restraint stress and keep the animal in place to gather the most reliable data.

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Description

To expand an existing system contact us. A representative from Bilaney Consultants will contact you to clarify the details. Several questions are listed below to assist you in describing the expansion. If you can include a serial number from the control box and/or a test station it would be helpful.

Do you want to add test stations? Please state type and number of current test stations and number of new test stations in Comment section. Also mention whether you are testing Rats, Mice or Both types. Do you want additional animal enclosures? Mouse: Small(20g), Small/Medium(50g) Rat: Medium(200g), Large(450g), Extra Large(850g). Do you want add on kits? Potentiated Startle KIt, Air Puff Kit, PPI-LED Light Kit, High Intensity Light Kit, PureTone Kit. Provide quantity desired and whether the kit is for Rats, Mice or Both types. Do you need replacement parts? Standardization Unit, Shock Grids, etc.

About

The SR-LABTM startle response system is the world’s most widely used startle reflex behavioral research system and the most successful for measuring startle habituationpre-pulse inhibition (PPI) and Fear Potentiated Startle (FPS).

Execute any and all startle reflex testing paradigms using the SR-LAB Software and specialized additional kits—and ensure accuracy using SR-LAB’s proprietary accelerometer which accommodates the rapid force changes in startle testing.

The only system of its kind that expands to 16 test stations, your SR-LAB™ will test a large number of animals at any given time. It will also test animals of varying sizes—from the smallest mouse to the largest rat using one of five sizes of easily changeable animal enclosures.

Highlights of the SR-LAB™ Startle Response System include:

Easily Test the Most Prevalent Test Paradigms

The basic SR-LAB System will test the Startle Habituation and Pre-Pulse Inhibition paradigms with no additional kits required.  To test the Fear Potentiated Startle paradigm, simply add on the SR-LAB Potentiated Startle Kit which includes the SDI Shocker (a proprietary design that keeps the animal from determining any patterns), a shock grid, and a cue light.  No additional software is required to support the Fear Potentiated Startle paradigm .

One Software Program for All Paradigms

With the SR-LAB software, you can develop and execute any startle reflex testing paradigm.  Other systems utilize different software for each paradigm which has two drawbacks: One—you will spend more money, and two—you have no flexibility in designing your own paradigms, and instead are limited to the paradigms offered by the manufacturer.

Be assured all trials are executed without missing any trials using SR-LAB’s concept of a Session containing Trials (discrete tests). Each session will run the animals through all the trials, and save all trial data for later analysis.

Other highlights of SR-LAB™’s software include:

  • Construct Trial Definitions with No Programming Required

    Define your trials to meet your specific needs by selecting commands from a wide range within a predefined menu.  Add, Insert or Delete commands to assure that the Trial definition is correct for your needs.

  • Point and Click to Set Session Level Parameters

    Set your session level parameters, construct trial lists, and set up Inter-Trial Intervals using SR-LAB’s simple point-and-click interface.

    Your session parameters can include number of samples, sample rate, background noise level, and repetitions. You can also define and edit sessions with the click of a mouse by inserting or removing Trials. In addition, edit or rename your sessions any time with ease.

    The ability to automatically randomize durations for Inter Trial Intervals assures that the animal will not discern a pattern that would skew results.

  • At-a-Glance Test Monitoring

    Monitor your test process at a glance by viewing response waveforms. Unlike other systems, the waveform visual gives you quick assurance that the calculated numbers are accurate.

  • Verify Data with Ease Using the SR-LAB Analysis Software

    Verify all of your startle response data with the SR-LAB Analysis Software. For each response, you can review the complete waveform to verify your numeric data.  Scoring parameters  you can set include Start Analysis, Analysis Range, Baseline and Response Window..  The SR-LAB Analysis Software also assures your calculated values are correct by allowing you to see, export, and use your raw data values.

  • Eliminate Concerns about Inaccurate Readings

    SR-LAB’s accelerometer is a key factor in the accuracy the system provides.  The sensor reacts very quickly to sudden force changes—assuring you get an accurate reading for the smallest mouse to the largest rat.  The accuracy provided by the sensor is aided by a complimentary enclosure design, which tightly couples the enclosure with the sensor.  Other systems use Load Cells which do not react as well to sudden force changes and also have limited ranges, requiring you to change load cells as animal weights change.

  • Avoid Stress-Induced Results

    The SR-LAB’s tubular enclosures are designed to allow the animals to turn around freely without constraint—thus avoiding restraint stress that can alter results. At the same time, the tubular design keeps animals over the sensor for reliable results. Your subjects will be monitored using an ultra-stable, hermetically sealed motion sensor that records a wide range of startle responses. Enclosures are designed with clear acrylic for easy cleaning and are available in five different sizes.

System components include:

  • Test cabinet in composite (ABS)
  • Standard animal enclosures in choice of five sizes or slotted animal enclosures for tethered animals in four sizes
  • Power supply
  • Input and Output cables
  • Software and User Manual
  • Software utilities for data analysis