Harvard Pump 11 Elite GC – Glucose Clamp Infusion System

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Harvard Apparatus offers a complete Glucose Clamp Infusion System for rats or mice including syringe pumps, swivels, tethers and catheters. Multiple syringe pumps push glucose, insulin and a drug, tracer glucose or other fluids into a 3 or 4-way connector which combines and reaches the animal via one channel of a dual channel swivel. Blood samples are taken manually or with an automated sampler on the second channel. The two-channel VAH simplifies the animal connection and PinPorts can be used to simplify injections or intermittent sampling.

  • 70-4504GC – Pump 11 Elite Infusion/Withdrawal Programmable Single Syringe Pump with Glucose Clamp Method [Request a Quote]
  • 70-4505GC – Pump 11 Elite Infusion/Withdrawal Programmable Dual Syringe Pump with Glucose Clamp Method [Request a Quote]
  • 70-4506GC – Pump 11 Pico Plus Elite Infusion/Withdrawal Programmable Dual Syringe Pump with Glucose Clamp Method [Request a Quote]
  • 70-4507GC – Pump 11 Elite Nanomite Infusion/Withdrawal Programmable Single Syringe Pump with Glucose Clamp Method [Request a Quote]
  • 70-4511GC – Pump 11 Pico Plus Elite Infusion/Withdrawal Programmable Single Syringe Pump with Glucose Clamp Method [Request a Quote]

Description

Pump 11 Elite GC Glucose Clamp Infusion System

Renowned syringe pump technology enhanced for academic euglycemic or hyperglycemic glucose clamp studies

The Pump 11 Elite Glucose Clamp Infusion System is a time saving syringe pump enhancement that offers quick and simple set-up using our innovative touch screen display. The built-in software capabilities reduce the potential for error in your research by providing the most accurate fluid delivery available.

  • Animal Weight, Concentration, and Dose Rate Programming: Glucose clamp method allows for the user to enter a desired concentration, animal weight, and dose rate into the syringe pump. The Pump 11 Elite uses that information to properly set the infusion rate automatically.
  • Change Dose Rate While Running: In the Glucose Clamp method, the user has the ability to change the dose rate during infusion. This allows the execution of complex infusion procedures without the need to start and stop the process.
  • Previous Dose Rate Display: The previous dose rate setting is displayed while the pump is running, which allows for easy monitoring. When the unit is stopped, the last dose rate set and its duration is clearly displayed.

Pump 11 Elite GC – Short Description

The Pump 11 Elite Glucose Clamp Infusion System, is a version of our renowned syringe pump technology enhanced for academic euglycemic or hyperglycemic glucose clamp studies.

The glucose clamp capabilities provide a time saving syringe pump enhancement that offers quick and simple set-up using our innovative touch screen display.

The built-in software capabilities reduce the potential for error in your research by providing the most accurate fluid delivery available.

The Pump 11 Elite Glucose Clamp Infusion System will simplify glucose clamp experiments with the following features.

1) Animal Weight, Concentration, and Dose Rate Programming

Glucose clamp method allows the user to enter in a desired concentration, animal weight, and dose rate in the syringe pump and then uses that information to set the infusion rate automatically.

2) Change Dose Rate While Running in the Glucose Clamp method

The user has the ability to change the dose rate during infusion. This allows the execution of complex infusion procedures without the need to start and stop the process.

3) Previous Dose Rate Display

The previous dose rate setting is displayed while the pump is running, which allows for easy monitoring. When the unit is stopped, the last dose rate set and its duration is clearly displayed.

Pump 11 Elite GC – Item Listing

Item# Description Pricing
70-4504GC Pump 11 Elite Infusion/Withdrawal Programmable Single Syringe Pump with Glucose Clamp Method Get a Quote
70-4505GC Pump 11 Elite Infusion/Withdrawal Programmable Dual Syringe Pump with Glucose Clamp Method Get a Quote
70-4506GC Pump 11 Pico Plus Elite Infusion/Withdrawal Programmable Dual Syringe Pump with Glucose Clamp Method Get a Quote
70-4507GC Pump 11 Elite Nanomite Infusion/Withdrawal Programmable Single Syringe Pump with Glucose Clamp Method Get a Quote
70-4511GC Pump 11 Pico Plus Elite Infusion/Withdrawal Programmable Single Syringe Pump with Glucose Clamp Method Get a Quote

Pump 11 Elite GC – Full Description

The Pump 11 Elite Glucose Clamp Infusion System, is a version of our renowned syringe pump technology enhanced for academic euglycemic or hyperglycemic glucose clamp studies.

The glucose clamp capabilities provide a time saving syringe pump enhancement that offers quick and simple set-up using our innovative touch screen display. The built-in software capabilities reduce the potential for error in your research by providing the most accurate fluid delivery available.

Features:

  • Intuitive Touch Screen with Glucose Clamp software
  • Program animal weight, concentration and dose rate without a PC
  • Ability to change dose rate while running
  • Previous dose rate display to simplify data recording
  • Icon operation
  • New color LCD touch screen
  • Vertical or horizontal orientation
  • Adjustable linear force to 11 or 35 lbs (depending on model) across the entire flow range
  • CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme Approved
  • 2-year warranty Applications:
  • Euglycemic and hyperglycemic glucose clamp studies
  • Drug/Nutritional infusions

The Pump 11 Elite Glucose Clamp Infusion System will simplify glucose clamp experiments with the following capabilities:

1) Animal Weight, Concentration, and Dose Rate Programming

Glucose clamp method allows the user to enter in a desired concentration, animal weight, and dose rate in the syringe pump and then uses that information to set the infusion rate automatically.

2) Change Dose Rate While Running in the Glucose Clamp method

The user has the ability to change the dose rate during infusion. This allows the execution of complex infusion procedures without the need to start and stop the process.

3) Previous Dose Rate Display

The previous dose rate setting is displayed while the pump is running, which allows for easy monitoring. When the unit is stopped, the last dose rate set and its duration is clearly displayed.

Pump 11 Elite GC – Specifications

Specifications 70-4504GC 70-4505GC 70-4506GC 70-4507GC 70-4511GC
Accuracy ±0.5% ±0.5% ±0.35% ±0.5% ±0.35%
Syringes 1 2 2 1 1
Flow Rate Minimum 1.26 pl/min 1.26 pl/min 0.54 pl/min 3.66 pl/min 0.54 pl/min
Flow Rate Maximum 88.4 ml/min 26.02 ml/min 11.7 ml/min 3.818 ml/min 39.77 ml/min
Classification Class I Class I Class I Class I Class I
Dimensions Control Box LxDxH in cm 9.0 x 7.0 x 6.0 (22.6 x 17.78 x 15.0) 9.0 x 7.0 x 6.0 (22.6 x 17.78 x 15.0) 9.0 x 7.0 x 6.0 (22.6 x 17.78 x 15.0) 9.0 x 7.0 x 3.67 (22.6 x 17.78 x 9.32) 9.0 x 7.0 x 6.0 (22.6 x 17.78 x 15.0)
Dimensions Remote Box LxDxH in cm N/A N/A N/A 2.5 x 2.0 x 7.5 (6.35 x 5.08 x 19.05) N/A
Display 4.3″ WQVGA TFT Color Display with Touchpad 4.3″ WQVGA TFT Color Display with Touchpad 4.3″ WQVGA TFT Color Display with Touchpad 4.3″ WQVGA TFT Color Display with Touchpad 4.3″ WQVGA TFT Color Display with Touchpad
Drive Motor 0.9° Stepper Motor 0.9° Stepper Motor 0.9° Stepper Motor 1.8° Stepper Motor 0.9° Stepper Motor
Environmental Humidity 20% to 80% RH, non condensing 20% to 80% RH, non condensing 20% to 80% RH, non condensing 20% to 80% RH, non condensing 20% to 80% RH, non condensing
Environmental Operating Temperature English 40°F to 104°F 40°F to 104°F 40°F to 104°F 40°F to 104°F 40°F to 104°F
Environmental Operating Temperature Metric 4°C to 40°C 4°C to 40°C 4°C to 40°C 4°C to 40°C 4°C to 40°C
Environmental Storage Temperatue English 14°F to 158°F 14°F to 158°F 14°F to 158°F 14°F to 158°F 14°F to 158°F
Environmental Storage Temperatue Metric -10°C to 70°C -10°C to 70°C -10°C to 70°C -10°C to 70°C -10°C to 70°C
I O TTL Connectors 15 pin D-Sub Connector 15 pin D-Sub Connector 15 pin D-Sub Connector 15 pin D-Sub Connector 15 pin D-Sub Connector
Input Power 12-30 VDC 12-30 VDC 12-30 VDC 12-30 VDC 12-30 VDC
Installation Category II II II II II
Max Linear Force 35 lbs at 100% Force 35 lbs at 100% Force 35 lbs at 100% Force 11 lbs at 100% Force 35 lbs at 100% Force
Mode of Operation Glucose Clamp Glucose Clamp Glucose Clamp Glucose Clamp Glucose Clamp
Motor Drive Control Microprocessor with 1/16 microstepping Microprocessor with 1/16 microstepping Microprocessor with 1/16 microstepping Microprocessor with 1/16 microstepping Microprocessor with 1/16 microstepping
Net Weight English 4.6 lb 4.6 lb 4.6 lb Control Box (4.32 lb)

Remote Mechanism (1.01 lb)

4.6 lb
Net Weight Metric 2.1 kg 2.1 kg 2.1 kg Control Box (1.96 kg)

Remote Mechanism (0.458 kg)

2.1 kg
No of Syringes 1 2 2 1 2
Non Volatile Memory Storage of all settings Storage of all settings Storage of all settings Storage of all settings Storage of all settings
Number of Microsteps per one rev of Lead Screw 15,360 15,360 20,480 3,200 20,480
Pollution Degree 1 1 1 1 1
Pump Configuration Single Dual Dual Single Dual
Pump Function Infuse/Withdraw, Programmable with Glucose Clamp Method Infuse/Withdraw, Programmable with Glucose Clamp Method Infuse/Withdraw, Programmable with Glucose Clamp Method Infuse/Withdraw, Programmable with Glucose Clamp Method Infuse/Withdraw, Programmable with Glucose Clamp Method
Pusher Travel Rate Maximum 159.8 mm/min 159.8 mm/min 71.55 mm/min 159.8 mm/min 71.55 mm/min
Pusher Travel Rate Minimum 0.18 µm/min 0.18 µm/min 0.068 µm/min 0.18 µm/min 0.68 µm/min
Regulatory Certifications CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme CE, ETL (UL, CSA), WEEE, EU RoHS, CB Scheme
Step Rate Maximum 26 µsec/ 26 µsec/ 26 µsec/ 52 µsec/ 26 µsec/
Step Rate Minimum 27.5 sec/µstep 27.5 sec/µstep 27.5 sec/µstep 27.5 sec/µstep 27.5 sec/µstep
Syringe Size Maximum 60 ml 10 ml 10 ml 1 ml 10 ml
Syringe Size Minimum 0.5 µl 0.5 µl 0.5 µl 0.5 µl 0.5 µl
USB Connectors Type B Type B Type B Type B Type B
Voltage Range 100-240 VAC, 50/60 Hz 100-240 VAC, 50/60 Hz 100-240 VAC, 50/60 Hz 100-240 VAC, 50/60 Hz 100-240 VAC, 50/60 H


Pump 11 Elite GC –
Journal Articles

Shichun Du, Hui Wu, Xiao Xu, Ying Meng, Fangzhen Xia, Hualing Zhai & Yingli Lu (2014 ) Tracing Fasting Glucose Fluxes with Unstressed Catheter Approach in Streptozotocin Induced Diabetic Rats  Journal of Diabetes Research

Hui Wu, Chunhua Sui, Hui Xu, Fangzhen Xia, Hualing Zhai, Huixin Zhang, Pan Weng, Bing Han, Sichun Du, and Yingli Lu (2014 ) The GLP-1 Analogue Exenatide Improves Hepatic and Muscle Insulin Sensitivity in Diabetic Rats: Tracer Studies in the Basal State and during Hyperinsulinemic-Euglycemic Clamp  Journal of Diabetes Research

Qin Fu, Bing Xu, Yongming Liu, Dippal Parikh, Jing Li, Ying Li, Yuan Zhang, Christian Riehle, Yi Zhu, Tenley Rawlings, Qian Shi, Richard B. Clark, Xiongwen Chen, E. Dale Abel & Yang K. Xiang (2014 ) Insulin Inhibits Cardiac Contractility by Inducing a Gi-Biased β2-Adrenergic Signaling in Hearts  Diabetes Journal

Harvard Apparatus Pump 11 Elite GC: Intuitive Touch Screen with Glucose Clamp Software – Program Animal Weight, Concentration and Dose Rate Without a PC – Ability to Change Dose Rate While Running Previous Dose Rate Display to Simplify Data Recording